WASHINGTON (AP) Heath officials on Tuesday authorized the first electronic cigarettes in the U.S., saying the R.J. Reynolds vaping products can benefit adult smokers.

The Food and Drug Administration said data submitted by the company showed its Vuse e-cigarettes helped smokers either quit or significantly reduce their use of cigarettes, the leading preventable cause of death in the U.S.

Tuesday’s first-of-a-kind decision is part of a sweeping effort by the FDA to bring scientific scrutiny to the multibillion-dollar vaping industry after years of delays.

In September, the agency said it had rejected applications for more than a million e-cigarettes and related products, mainly due to their potential appeal to underage teens. But regulators delayed making decisions on most of the major vaping companies, including market leader Juul.

The FDA’s decision only applies to Vuse’s refillable Solo Power device and its tobacco-flavored nicotine cartridges. The FDA said it rejected 10 other requests from the company for other flavored products, but did not disclose details. The agency is still reviewing the company’s request to sell a menthol-flavored nicotine formula.

“Today’s authorizations are an important step toward ensuring all new tobacco products undergo the FDA’s robust, scientific premarket evaluation,” said Mitch Zeller, director of the FDA’s tobacco center, in a statement.

“The manufacturer’s data demonstrates its tobacco-flavored products could benefit addicted adult smokers who switch to these products - either completely or with a significant reduction in cigarette consumption.”

To stay on the market, companies must show that their products benefit public health.